Fibromyalgia: a general inflammation

It has been an important step in understanding the mechanisms involved in fibromyalgia, particularly as it relates to the inflammatory process.

It has already been suggested that chronic inflammation likely plays a central role in fibromyalgia, says the Swedish team (universities of Uppsala and Linköping).

However, previous studies have focused on some inflammatory molecules called cytokines features.

Here, researchers have searched simultaneously hundred proteins associated with the inflammatory process, and this in blood and cerebrospinal fluid (swimming in the brain and spinal cord).

They performed these tests in patients with fibromyalgia and people without the disease.

The result highlights “strong” evidence of a dual phenomenon in fibromyalgia: neuroinflammatory (CSF) and chronic inflammatory systemic (blood).

In other words, inflammation is widespread. Two cytokines are: fractalkine and Interleukin-8 (IL-8).

The important point is the commentary of specialists: “This is the first time an inflammatory profile also expanded described for fibromyalgia, which seems characterized by objective biochemical alterations”.

This is to say that “the description of its mechanisms essentially idiopathic (cause unknown) or even psychological be considered outdated.”

They add that further exploration of inflammatory processes should help identify ways to more selective and more effective treatments.

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